Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dbx1  developing brain homeobox 1   (Synonyms: Dbx, Mmox C)
Results	Reference
1	J:150524 Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA, Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nat Neurosci. 2009 Apr;12(4):409-17
1*	J:89228 Chen MH, Li YJ, Kawakami T, Xu SM, Chuang PT, Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates. Genes Dev. 2004 Mar 15;18(6):641-59
1	J:206591 Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A, Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity. Development. 2014 Jan;141(2):377-88
1	J:252092 Gard C, Gonzalez Curto G, Frarma YE, Chollet E, Duval N, Auzie V, Aurade F, Vigier L, Relaix F, Pierani A, Causeret F, Ribes V, Pax3- and Pax7-mediated Dbx1 regulation orchestrates the patterning of intermediate spinal interneurons. Dev Biol. 2017 Dec 1;432(1):24-33
1	J:147382 Genethliou N, Panayiotou E, Panayi H, Orford M, Mean R, Lapathitis G, Malas S, Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord. Biochem Biophys Res Commun. 2009 Apr 24;382(1):69-73
1	J:125693 Hanashima C, Fernandes M, Hebert JM, Fishell G, The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes. J Neurosci. 2007 Oct 10;27(41):11103-11
1*	J:119875 Lebel M, Mo R, Shimamura K, Hui CC, Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
1*	J:2257 Lu S, Bogarad LD, Murtha MT, Ruddle FH, Expression pattern of a murine homeobox gene, Dbx, displays extreme spatial restriction in embryonic forebrain and spinal cord. Proc Natl Acad Sci U S A. 1992 Sep 1;89(17):8053-7
1	J:291948 Ma P, Song NN, Cheng X, Zhu L, Zhang Q, Zhang LL, Yang X, Wang H, Kong Q, Shi D, Ding YQ, Mao B, ZC4H2 stabilizes RNF220 to pattern ventral spinal cord through modulating Shh/Gli signaling. J Mol Cell Biol. 2020 Jun 11;12(5):337-344
1	J:291960 Ma P, Song NN, Li Y, Zhang Q, Zhang L, Zhang L, Kong Q, Ma L, Yang X, Ren B, Li C, Zhao X, Li Y, Xu Y, Gao X, Ding YQ, Mao B, Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning. Cell Rep. 2019 Jul 9;28(2):541-553.e4
1*	J:41030 Mastick GS, Davis NM, Andrew GL, Easter SS Jr, Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain. Development. 1997 May;124(10):1985-97
1*	J:43464 Matise MP, Joyner AL, Expression patterns of developmental control genes in normal and Engrailed-1 mutant mouse spinal cord reveal early diversity in developing interneurons. J Neurosci. 1997 Oct 15;17(20):7805-16
1	J:86051 Muller M, Jabs N, Lork DE, Fritzsch B, Sander M, Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons. Development. 2003 Dec;130(23):5815-26
1	J:240032 Nouri N, Awatramani R, A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons. Development. 2017 Mar 01;144(5):916-927
1	J:121344 Pachikara A, Dolson DK, Martinu L, Riccomagno MM, Jeong Y, Epstein DJ, Activation of Class I transcription factors by low level Sonic hedgehog signaling is mediated by Gli2-dependent and independent mechanisms. Dev Biol. 2007 May 1;305(1):52-62
1	J:80207 Persson M, Stamataki D, te Welscher P, Andersson E, Bose J, Ruther U, Ericson J, Briscoe J, Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Dev. 2002 Nov 15;16(22):2865-78
1	J:56241 Pierani A, Brenner-Morton S, Chiang C, Jessell TM, A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord. Cell. 1999 Jun 25;97(7):903-15
1	J:152847 Prakash N, Puelles E, Freude K, Trumbach D, Omodei D, Di Salvio M, Sussel L, Ericson J, Sander M, Simeone A, Wurst W, Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain. Development. 2009 Aug;136(15):2545-55
1	J:168317 Qin J, Lin Y, Norman RX, Ko HW, Eggenschwiler JT, Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1456-61
1*	J:103820 Reiter JF, Skarnes WC, Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 1;20(1):22-7
1	J:327338 Sartoretti MM, Campetella CA, Lanuza GM, Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling. Development. 2022 Aug 1;149(15):dev200750
1*	J:33698 Shoji H, Ito T, Wakamatsu Y, Hayasaka N, Ohsaki K, Oyanagi M, Kominami R, Kondoh H, Takahashi N, Regionalized expression of the Dbx family homeobox genes in the embryonic CNS of the mouse. Mech Dev. 1996 May;56(1-2):25-39
1	J:345248 Tran HN, Nguyen QH, Jeong Y, Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi. Front Cell Dev Biol. 2024;12:1336308
1	J:323216 Wang YB, Song NN, Zhang L, Ma P, Chen JY, Huang Y, Hu L, Mao B, Ding YQ, Rnf220 is Implicated in the Dorsoventral Patterning of the Hindbrain Neural Tube in Mice. Front Cell Dev Biol. 2022;10:831365